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  •  SIStemA


    Cell type :

    hESCHuman Embryonic Stem Cells
    hiPSCHuman Induced Pluripotent Stem Cells
    LGELateral Ganglionic Eminence
    MGEMedial Ganglionic Eminence
    MSCMesenchymal Stem Cells
    NSCNeural Stem Cells
    RPERetinal Pigment Epithelium


    Phenotype :

    ATRA Hutchinson-Gilford syndrome ORPHA:740
    DM1 Myotonic Dystrophy type I ORPHA:273
    DMD Duchenne Muscular Dystrophy ORPHA:98896
    EB Epidermolysis bullosa ORPHA:304
    HD Huntington disease ORPHA:399
    LND Lesch Nyhan Disease ORPHA:510
    SMA Spinal muscular atrophy ORPHA:83330
    WFS Wolfram Syndrome ORPHA:3463
    WT Non affected
    E3 CRISPR MBNL1 (-/-)
    H4 CRISPR MBNL1 (-/-) MBNL2 (-/-)


    Time of differentiation :

    DIV Day In Vitro: number of day in vitro culture after differentiation and before collection of the sample
    P Passage: term representing the number of passage before the hESC/hIPSC sample is collected or used for differentiation. Depending on the cell line, a passage corresponds to 5 or 7 days


    Treatment :

    KOGene Knock-Out, cells with a loss-of-function mutation in a gene.
    KIGene Knock-In


    Matrix :

    MEFMouse Embryonic Fibroblasts
    POPoly-L-Ornithine
    LAMLaminine
    FBFibronectine


    Other :

    GFPGreen Fluorescent protein