NGS Platform
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Mat&Meth
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SIStemA
Single Gene
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Cell type :
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Brain Neuronal cells
hESC-derived Cortex progenitors (3)
hESC-derived Cortical Neuron (5)
hESC-derived dopaminergic Neuron (2)
hESC-derived LGE-like progenitors (26)
hESC-derived MGE-like progenitors (1)
hESC-derived neural progenitor (31)
hESC-derived Neuron (9)
hESC-derived striatal neurons (28)
hESC-derived Telencephalic Rosette_NSC (4)
hiPSC-derived Cortical Neurons (16)
hiPSC-derived dopaminergic Neuron (5)
hiPSC-derived dopaminergic Neuron progenitor (7)
hiPSC-derived Neuron (23)
hiPSC-derived NSC (12)
hiPSC-derived striatal neurons (22)
hES hiPS cells
hESC (24)
hiPSC (21)
metaSample hESC median (1)
metaSample hiPSC median (1)
Mesenchymal Stem cells
hESC-hiPSC-derived MSC (6)
Motoneurons
hiPSC-derived Motoneuron (39)
Myogenic cells
hiPSC-derived Mesoderm precursor (12)
hiPSC-derived Myotube (12)
Primary Myoblast (6)
Primary Myoblast-derived Myotube (10)
Reference cells
Adult Human Whole Brain tissus (1)
Human Adult Brain cerebral cortex tissus (1)
Human Adult Brain total tissus (1)
Human Adult Caudate tissus (2)
Human Adult Cortex tissus (1)
Human Adult striatum tissus (1)
Human Fœtal tissus (1)
Human Fœtal tissus Cortex (3)
Human Fœtal tissus LGE (6)
Human Fœtal tissus MGE (3)
Reference melanocyte - mel 311 P5 Lonza (2)
Reference melanocyte - mel 663 P5 Lonza (1)
Reference melanocyte - mel 704 P5 Lonza (1)
Retinal pigment epithelium cells
hESC-derived RPE (12)
hiPSC-derived RPE (29)
Skins cells
Fibroblasts (15)
hESC-derived Melanocyte (33)
hiPSC-derived Keratinocyte (6)
Phenotype :
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ATAR Hutchinson-Gilford Syndrome -
ORPHA:740
(3)
DM1 Myotonic Dystrophy type I -
ORPHA:273
(3)
DMD Duchenne Muscular Dystrophy -
ORPHA:98896
(17)
EB Epidermolysis bullosa simplex -
ORPHA:304
(3)
HD Hungtington Disease -
ORPHA:399
(39)
LND Lesch Nyhan Disease -
ORPHA:510
(8)
SMA Spinal Muscular Atrophy -
ORPHA:83330
(18)
WFS Wolfram Syndrome -
ORPHA:3463
(25)
WT Non affected (323)
WT_CRISPR MBNL1 (3)
WT_CRISPR MBNL1/2 (3)
Cell line :
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13-01 (4)
13-02 (4)
13-11 (6)
14-05 (5)
14-27 (5)
1869c07 (3)
2227c02 (2)
232-11 (3)
232-11 14-27 (3)
232-7 (1)
23784c05 (2)
2851c15 (2)
2852c03 (2)
4603c45 (9)
56c02 (7)
56c02_CRISPR MBNL1 (3)
56c02_CRISPR MBNL1/2 (3)
61c7 (3)
H9 (1)
HD1 (19)
I90cl17 (6)
M180 (4)
M194 (4)
M197 (4)
M202 (8)
M313 (1)
M398 (4)
M418 (4)
NA (45)
NAMAD (1)
PB12c03 (3)
PB12c13 (3)
PC085 (1)
PC1432 (1)
PC15 (1)
RC17 (2)
RC9 (81)
SA001 (93)
V1024 (10)
VUB01 (4)
WS1 (2)
WS2 (12)
WS5 (11)
delta60 (20)
i90cl16 (23)
i90cl17 (3)
metaSample (2)
1869 (3)
9991 (1)
10295 (1)
Time of differentiation :
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DIV1 (16)
DIV10 (34)
DIV14 (16)
DIV17 (4)
DIV18 (13)
DIV2 (3)
DIV20 (10)
DIV21 (24)
DIV25 (7)
DIV28 (9)
DIV3 (6)
DIV32 (6)
DIV34 (6)
DIV35 (12)
DIV4 (21)
DIV40 (3)
DIV43 (6)
DIV44 (43)
DIV45 (12)
DIV46 (13)
DIV49 (12)
DIV54 (1)
DIV54-P4 (3)
DIV54-P7 (3)
DIV55 (8)
DIV7 (4)
NA (132)
P10 (11)
P11 (5)
P9 (2)
Treatment & Time (derived) :
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ATRA 10µM (3)
CRISPR gene editing KO MBNL1 (3)
CRISPR gene editing KO MBNL1/2 (3)
DMSO 0.1 % (3)
DMSO mM 24h (3)
KI Ctrl (Lenti-virus) (3)
KI DKIN WT gene DIV35 (Lenti-virus) (4)
KI DKIN mutated gene DIV35 (Lenti-virus) (4)
KI mutated HTT gene (Lenti-virus) (3)
KO HTT gene (Lenti-virus) (29)
KO HTT gene DIV29 (Lenti-virus) (3)
Kenpaulone – 10 microM (10)
Lenti-virus Ctrl (3)
Lenti-virus Ctrl (GFP) DIV35 (4)
Lenti-virus Ctrl (Luciferase) (15)
Lenti-virus Ctrl (Luciferase) DIV29 (3)
Lithium 0.5 mM 24h (3)
Microfluidic chip (16)
NA (280)
Thapsigargin 8h (5)
VPA 0.5 mM (4)
VPA 1 mM (1)
VPA 1.5 mM (6)
VPA 3mM 24h (3)
alpha-SGmutated (R77C) overexpression - DMSO 0.1% - 24h (3)
alpha-SGmutated (R77C) overexpression - MG132 1 microM - 24h (3)
alpha-SGmutated (R77C) overexpression - Thiostrepton 3 microM - 24h (3)
alpha-SGmutated (R77C) overexpression - Thiostrepton 5 microM - 24h (3)
alpha-SGmutated (R77C) overexpression - bortezomib 30 nM - 24h (3)
hIPSC-derived Cortical Neurons on microfluidic chip connected to hIPSC-derived MSN (4)
hIPSC-derived striatal neurons on microfluidic chip connected to hIPSC-derived Cortical Neurons (4)
hIPSC-derived striatal neurons on microfluidic chip connected to hIPSC-derived Cortical Neurons and dopaminergique antagonist D2 (8)
Target gene :